Exeter came from 26-6 down to secure a dramatic 27-26 win and inflict a rare home defeat on Sale as the Gallagher PREM resumed.
Leicester Tigers eked out a 36-35 win against Sale Sharks as Bath, Harlequins and Exeter all won by big scorelines in Saturday's Gallagher Prem action.
Finn Russell led Bath to a bonus-point 38-17 victory over Gloucester on his return to the team.
Exeter chair Tony Rowe has suspended coaches Rob Hunter and Ali Hepher following the Chiefs' record Gallagher Premiership defeat against Gloucester.
London Irish administrator Lee Manning says it is only "a matter of time" until the next Premiership club goes bust and that "radical change" is needed.
Alex Cuthbert chats exclusively to Sky Sports about his career and 2013 British and Irish Lions tour memories as part of our Lions Recollections digital series.
England wing Immanuel Feyi-Waboso will miss the entire Six Nations because of the dislocated shoulder sustained on club duty for Exeter last month.
Exeter claimed their first Gallagher Premiership victory of the season as they edged out West Country rivals Gloucester 22-15 at Sandy Park.