Exeter came from 26-6 down to secure a dramatic 27-26 win and inflict a rare home defeat on Sale as the Gallagher PREM resumed.
Leicester Tigers eked out a 36-35 win against Sale Sharks as Bath, Harlequins and Exeter all won by big scorelines in Saturday's Gallagher Prem action.
Finn Russell led Bath to a bonus-point 38-17 victory over Gloucester on his return to the team.
Exeter chair Tony Rowe has suspended coaches Rob Hunter and Ali Hepher following the Chiefs' record Gallagher Premiership defeat against Gloucester.
London Irish administrator Lee Manning says it is only "a matter of time" until the next Premiership club goes bust and that "radical change" is needed.
Alex Cuthbert chats exclusively to Sky Sports about his career and 2013 British and Irish Lions tour memories as part of our Lions Recollections digital series.
England wing Immanuel Feyi-Waboso will miss the entire Six Nations because of the dislocated shoulder sustained on club duty for Exeter last month.
Exeter claimed their first Gallagher Premiership victory of the season as they edged out West Country rivals Gloucester 22-15 at Sandy Park.
A round-up of Saturday's Investec Champions Cup action, where Northampton and Saracens made winning starts but Exeter were beaten by Sharks in South Africa.
Defending champions Northampton suffered a shock defeat to Gloucester, while Bath returned to top of the Premiership and Sale beat Leicester.
Henry Slade proved his fitness ahead of England's Autumn Nations Series opener but could not prevent Exeter from suffering defeat by Harlequins.
Northampton bounced back from their derby disappointment in style as they trounced Sale while Newcastle earned their first Premiership victory in over a year.
Leicester made it three wins from four under Michael Cheika as they beat rivals and defending champions Northampton 24-8 on Saturday.
England back row Ben Earl scored two tries as Saracens made it three wins from three in the Premiership this season with a 29-14 victory over Exeter.
Wales lock Dafydd Jenkins looks increasingly unlikely to be fit for the autumn internationals.
Leigh Halfpenny celebrated a first Gallagher Premiership try as Harlequins picked up a 28-14 bonus-point victory over Newcastle at Twickenham Stoop.
Michael Cheika's reign as Leicester head coach began in dramatic winning fashion as the Tigers claimed a 17-14 Gallagher Premiership victory at Sandy Park.
Ahead of Saturday's Northampton Saints vs Bath Premiership final at Twickenham, Sky Sports looks back at the greatest witnessed so far...
A man is to be charged with racially aggravated harassment of former England rugby union international Ugo Monye.
Championship clubs have welcomed the approval of promotion to the Gallagher Premiership as a "new era" for the professional game in England.