Matias Fernandez's first goal for AC Milan was enough to earn them a 1-0 home win against Serie A rivals Genoa.
Sampdoria scored a historic 1-0 derby victory against Genoa in Serie A's only match on Saturday.
Juventus now lead Serie A by eight points after drawing 1-1 at Udinese on Sunday, while Lazio and Inter Milan both claimed away wins.
Roma closed the gap on Serie A leaders Juventus to seven points with a 3-1 win away to Inter Milan at San Siro.
Napoli moved up to second in the Serie A table with a 2-0 home victory over strugglers Genoa.
Juan Cuadrado's thunderbolt gave Juventus 1-0 home win over Inter Milan on Sunday, as Sampdoria beat AC Milan and Lazio hit six.