Davinson Sanchez and Kasper Dolberg both scored twice as Ajax beat Zwolle 5-1 while PSV won at Excelsior.
On-loan Manchester City teenager Enes Unal scored twice as FC Twente beat Den Haag 4-1 in their Eredivisie clash at De Grolsch Veste.
Feyenoord maintained their perfect start to the season, while there were wins for Ajax and Go Ahead Eagles in the Eredivisie on Sunday.
PSV Eindhoven surrendered their 100 per cent record in disappointing fashion after being held to a 0-0 draw at home to Groningen.
Feyenoord continued their perfect start to the season and returned to the top of the Eredivisie with a 1-0 win at Heracles Almelo.
Eredivisie champions PSV made it two wins from two as Hector Moreno's goal secured a 1-0 victory over AZ Alkmaar, on Sunday.