Reigning women's Challenge Cup winners St Helens will face Castleford Tigers, Warrington Wolves and London Broncos as they look to complete a hat-trick of wins.
The Saints, who beat the Leeds Rhinos in 2022, are one of 16 teams battling it out for a spot in the final at Wembley on August 12 as the men's and women's finals take place at the same venue for the first time.
The draw for both the men's and women's competitions took place at Wembley on Thursday evening, St Helens women's Eboni Partington and Wigan men's Kai Pearce-Paul representing their sides as current Challenge Cup holders.
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The women's draw saw the 12 Super League sides pooled alongside four Championship teams, St Helens, Leeds, Wigan, and York Valkyrie entering the pools as the top seeds.
Group One sees Wigan Warriors battle it out against Featherstone Rovers, Salford Red Devils, and Cardiff Demons, Group Two pitting Leeds Rhinos against Huddersfield Giants, Bradford Bulls and Oulton Raidettes.
St Helens headline Group Three alongside the aforementioned Warrington Wolves, Castleford Tigers, and London Broncos, with York Valkyrie, Barrow Raiders, Leigh Leopards, and Hull KR making up Group Four.
The women's competition will get under way from April 23.
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In the first round of the men's competition, a Wigan derby is the highlight fixture when Wigan St Patricks face local rivals Ince Rose Bridge as the 36 community teams get the tournament under way.
There is also a clash between two Leeds sides in the first round as Stanningley take on fellow Yorkshire residents Milford.
The second round sees 10 teams from the National Conference League Premier Division and 10 teams from League One join the action and there is the potential for another Leeds derby as League One side Hunslet will face either Heworth or Oulton Raiders.
The second round also sees some history in the making as League One side Cornwall RLFC make their Challenge Cup debut with a clash against Rochdale Mayfield, a year after forming as a club.
The men's competition begins on February 11.
Sky Sports is the home of all three Super League Grand Finals in 2023. The Men's Grand Final, the Women's Grand Final and the Wheelchair Grand Final will all be live on Sky Sports next season. The new Super League season starts on Thursday February 16 when Warrington Wolves take on Leeds Rhinos.