Two-time European winners Munster were dumped out of the Champions Cup at the pool stage for just the fourth time since 1998 as they were stunned by Castres at Thomond Park 31-29.
Bristol ran riot in a remarkable first half to secure their place in the Investec Champions Cup knockout phase with a 61-49 victory over the Bulls in Pool Four in Pretoria.
A late converted try from Kalaveti Ravouvou proved just enough for Bristol to maintain their winning run with a 19-17 victory as Sale lost on the road in the Gallagher Prem for a sixth consecutive game.
Sale emphatically ended a run of four straight Prem Rugby defeats by thumping fellow strugglers Harlequins 43-17 in a bonus-point win at the CorpAcq Stadium in Salford.
Munster bounced back from a disappointing defeat to Bath last week to comprehensively beat Gloucester 31-3 in the Champions Cup at Páirc Uí Chaoimh in Cork.
Glasgow stormed back from a 14-point deficit to open their Champions Cup campaign with a 26-21 victory at Sale Sharks.
England flanker Tom Curry will not face disciplinary action following his alleged tunnel bust-up with Argentina head coach Felipe Contepomi.
Exeter came from 26-6 down to secure a dramatic 27-26 win and inflict a rare home defeat on Sale as the Gallagher PREM resumed.