Cardiff Blues hooker Matthew Rees has been handed a seven-week ban for stamping on Nick Easter of Harlequins.
A Mark Wilson hat-trick and four tries from Marcus Watson eased Newcastle to a 55-7 victory against Enisei-STM.
There were wins for Sale and Connacht in the Challenge Cup on Saturday while London Irish lost away to Grenoble.
Edinburgh made it two wins out of two in Challenge Cup Pool 5 with a 27-6 success in Agen.
World Cup winner Ben Franks could make his London Irish debut in Saturday's Challenge Cup trip to Grenoble.
Cardiff Blues marked Jonah Lomu's death with one minute of applause ahead of their Challenge Cup against Harlequins.
Blues hooker Matthew Rees was shown a straight red card for stamping on the head of Nick Easter in the Challenge Cup.
Team news as Agen host Edinburgh and Montpellier square off with Calvisano in the Challenge Cup on Friday.
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