Harlequins host the first of at least 40 live games from The European Champions Cup and Challenge Cup on Sky Sports.
European Challenge Cup holders Gloucester will face local rivals Worcester Warriors in the 2015-16 competition.
Gloucester will play their first play-off fixture at home as they chase a spot in next season's European Champions Cup.
Friday's European Challenge Cup final could be the game of the weekend, says Dewi Morris.
Jonny May says Gloucester 'did it for the city' when they beat Edinburgh 19-13 in the Challenge Cup final on Friday.
Greig Laidlaw says there will be no conflict of emotions when he runs out on Friday to face his former club Edinburgh.
Gloucester return to the scene of their 2006 Challenge Cup success in Friday's final against Edinburgh at the Stoop.
Billy Twelvetrees says victory in the European Challenge Cup final on Friday night will be "a huge bonus" for Gloucester.
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