Rangers hope a 2-0 lead will be enough as they look to exorcise the Europa League ghosts of 2017 after missing the chance to kill off Progres Niederkorn at Ibrox.
Live updates from Molineux where Wolves' Europa League campaign gets underway in the second qualifying round against Crusaders.
Leigh Griffiths scored on his return as Celtic took command of their second Champions League qualifier with a 5-0 first-leg win over Nomme Kalju.
Wolves could face either Pyunik of Armenia or Czech side Jablonec in the Europa League qualifying draw.
Kilmarnock suffered a shock 2-0 defeat to Connah's Quay Nomads at Rugby
Park in the Europa Leaque qualifying first round on Thursday night.
Rangers set up a Europa League revenge mission with Progres Nieiderkorn as they routed St Joseph's 6-0 at Ibrox.
Kilmarnock manager Angelo Alessio is anticipating a great atmosphere with "noise and passion" from fans in his first home game at Rugby Park.
Stuart Findlay headed a last-gasp winner as Kilmarnock snatched a 2-1 victory in the Europa League first qualifying round first leg against Connah's Quay.
Sam Cosgrove scored a hat-trick as Aberdeen sealed their place in the third qualifying round of the Europa League with a 5-0 win over Georgian side Chikhura Sachkhere.
Sheyi Ojo hit a debut goal as Rangers beat St Joseph’s 4-0 in their Europa League opener following a goalless first half in Gibraltar.
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