Juventus are closing in on a fifth consecutive Serie A title after emerging victorious from a gritty game with Fiorentina.
Simone Inzaghi has been appointed as Lazio head coach after Stefano Pioli was sacked following Sunday's derby defeat to Roma.
Juventus have moved a step closer to a record-equalling fifth successive Serie A title after their closest rivals Napoli lost at Udinese.
Gary Neville was sent to the stands as Valencia lost to Athletic Bilbao in the Europa League, while Sparta Prague stunned Lazio.
Gonzalo Higuain's penalty saw Napoli squeeze past Palermo 1-0 and maintain their pursuit of the Serie A title.
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Gary Neville's Valencia lost 1-0 at Athletic Bilbao, while Shakhtar Donetsk, Villarreal and Fenerbahce also won in the Europa League.
Juventus restored their three-point advantage at the top of Serie A with a 2-0 win at Atalanta on Sunday.
Fiorentina played out a 1-1 draw with Napoli, while Sassuolo beat Lazio 2-0 in Serie A on Monday.
Gary Neville's Valencia smashed a Europa League record with the biggest aggregate win in the competition's history.
Felipe Anderson's agent has backed up claims that Manchester United have not been in contact about the Lazio winger.
Lazio have dismissed reports they have agreed to sell Brazilian playmaker Felipe Anderson to Manchester United in the summer.
Roma routed Palermo without Francesco Totti on Sunday, while Fiorentina kept pace in the Serie A title race.
Gary Neville enjoyed the perfect birthday as Valencia thrashed Rapid Vienna 6-0 their Europa League last-32 tie at the Mestalla.
Fiorentina had Matias Fernandez sent off as they drew 1-1 with Bologna in Serie A on Saturday.
Crystal Palace are bottom of the Europe-wide form table - and only one Premier League team makes the top 10.
Lazio have been fined £38,000 and forced to close parts of their stadium for the next two home games.
Lazio's match with Napoli was halted for around three minutes after supporters aimed abuse at Kalidou Koulibaly.
Ten-man Juventus needed an own goal from Genoa defender Sebastian De Maio to maintain their pursuit of Serie A leaders Napoli.
Carlos Bacca and M'Baye Niang hit second-half goals as AC Milan beat Inter Milan 3-0 on Sunday.