Northampton Saints were brought back down to earth after they suffered a 50-28 loss away to Champions Cup holders Bordeaux in a repeat of last season's final.
Bath lost a 26-point lead in an epic south-west derby only to snatch back victory in the most dramatic fashion in the closing seconds to beat Exeter 33-26, before Northampton Saints returned to the top of the Prem table.
Sale emphatically ended a run of four straight Prem Rugby defeats by thumping fellow strugglers Harlequins 43-17 in a bonus-point win at the CorpAcq Stadium in Salford.
Munster bounced back from a disappointing defeat to Bath last week to comprehensively beat Gloucester 31-3 in the Champions Cup at Páirc Uí Chaoimh in Cork.
An astonishing start which saw Bath 28-0 ahead inside 19 minutes proved crucial as the Prem side saw off Munster 40-14 in their Champions Cup opener.
Gloucester beat Harlequins 26-15 at Kingsholm to record their first Prem win of the season at the sixth attempt.
Leicester Tigers eked out a 36-35 win against Sale Sharks as Bath, Harlequins and Exeter all won by big scorelines in Saturday's Gallagher Prem action.
Marcus Smith's return inspired Harlequins to their first win of the Prem season as Saracens saw their perfect start come to an end with a 20-14 loss at The Stoop.
Leicester staged an incredible fightback to beat Harlequins, whilst Exeter beat Newcastle, and Saracens took control of Bristol.
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London Irish administrator Lee Manning says it is only "a matter of time" until the next Premiership club goes bust and that "radical change" is needed.
Danny Care chats to Sky Sports about England highs and lows, his incredible longevity in the sport and despair at never becoming a British and Irish Lion.
The rest of the Six Nations must "watch out" for an England side who have learned hard lessons under Steve Borthwick, according to Harlequins scrum-half Danny Care.
Former England scrum-half Danny Care has revealed he will complete his 20th season at Harlequins by staying at the club for another year.
Harlequins ended their three-game winless run in the Gallagher Premiership with a 38-14 victory over Newcastle at Kingston Park.
Bath inflicted a record Gallagher Premiership defeat on 14-man Saracens as they powered to a 68-10 victory at the Recreation Ground.
Gloucester beat an out-of-sorts Harlequins at Kingsholm as the visitors were blanked in a league game for the first time in a decade.
Northampton overcame the loss of injured captain George Furbank to post a statement 30-21 Investec Champions Cup win against the Bulls in Pretoria.
Marcus Smith has signed a new long-term contract that will keep him at Harlequins until at least 2028.
Harlequins said goodbye to Joe Marler and their reputation as one of the Gallagher Premiership's meanest defences as irresistible Bristol stormed The Stoop 48-24.