Harlequins defied their abysmal domestic form to stun La Rochelle 27-17 at Stade Marcel Deflandre and secure home advantage in the Champions Cup round of 16.
Bristol ran riot in a remarkable first half to secure their place in the Investec Champions Cup knockout phase with a 61-49 victory over the Bulls in Pool Four in Pretoria.
As reports continue to circulate the Welsh Rugby Union intend to cut one of their four regions from the professional game, Ospreys and Cardiff posted Boxing Day derby victories over Scarlets and Dragons.
Munster bounced back from a disappointing defeat to Bath last week to comprehensively beat Gloucester 31-3 in the Champions Cup at Páirc Uí Chaoimh in Cork.
An astonishing start which saw Bath 28-0 ahead inside 19 minutes proved crucial as the Prem side saw off Munster 40-14 in their Champions Cup opener.
Prop Henry Thomas and hooker Evan Lloyd have both been included for their first Test starts in Wales' Six Nations side to take on France in Paris on Friday.
Warren Gatland has named four uncapped players in Wales' squad to take on South Africa and Australia this summer.
Ken Owens has announced his retirement from rugby on medical grounds, after a successful career representing Scarlets, Wales and the British and Irish Lions.