Courtney Lawes has withdrawn from England's Six Nations squad due to take on France, while Marcus Smith has been retained over George Ford in the 27-player group.
Julian Montoya scored two tries to lead Leicester Tigers to a big win over Bath, while Harlequins record dominant victory over Exeter.
MPs have warned the financial situation of Premiership clubs is "clearly unsustainable" in a damning report on issues facing the game in England.
A round-up of Sunday's Heineken Champions Cup action as Edinburgh booked a last-16 place after victory at Castres, while Stormers and Racing 92 won.
A round-up of Sunday's Gallagher Premiership action as Sale Sharks proved too strong for Harlequins, with London Irish cruising past Bristol Bears....
Joe Marler has apologised again for his comments to Jake Heenan, adding his wife said: "Why am I defending you? Just stop doing it"
Round-up of Saturday's Gallagher Premiership action as Northampton Saints beat 14-man Saracens and Harlequins defeated Newcastle Falcons.
Northampton emphatically ended a run of four successive defeats in the Gallagher Premiership and Champions Cup by beating Harlequins 46-17 at Franklin's Gardens.
Harlequins prop Joe Marler has been handed a two-week ban for comments made towards Bristol flanker Jake Heenan during the sides' Premiership match.
Bristol defied a second-half onslaught from Harlequins to claim a 15-12 win at the Stoop that lifts them off the foot of the Premiership.
Harlequins avenged their harrowing home defeat by Racing 92 two years ago by dispatching the French heavyweights 14-10 in their Heineken Champions Cup clash.
Harlequins fell to defeat at South African side Sharks in their opening Heineken Champions Cup game as Leinster and Gloucester started with victories.
Harlequins reeled off a fourth successive Premiership victory after halting Bath's recent resurgence by winning 19-13 at The Rec.
England's Marcus Smith will not play again this year after suffering an ankle injury during the autumn finale against South Africa.
Joe Launchbury has signed for Harlequins on a multi-year deal and will join the Gallagher Premiership club in the summer following a stint in Japan.
Recap Saturday's Premiership action as Harlequins beat London Irish late in a fiery derby, while Northampton were too strong for Bristol.
Marcus Smith proved the difference for Harlequins as they put an end to Sale's unbeaten start in the Premiership this season.
Leicester's Tommy Reffell issued a timely reminder to Wales coach Wayne Pivac by scoring twice in his side's 27-19 win over Harlequins.
Premiership Rugby wants to introduce an independent regulator to oversee clubs' finances.
Worcester Warriors' matches against Gloucester and Harlequins have been cancelled as four players head to Bath on loan.
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