Exeter snatched a second successive home win with the last play of the game to thwart Harlequins' stunning second-half comeback.
Exeter ensured there was no fairytale ending to a turbulent week for beleaguered Worcester as they claimed a 36-21 Premiership win at Sixways.
Here's what happened on the opening day of the Gallagher Premiership season.
Exeter have signed Australia international prop Scott Sio on a long-term contract from Super Rugby side the Brumbies.
Premiership Rugby has taken its first step towards "greater transparency" by publishing a salary cap report for the 2020-21 season.
Leicester Tigers have become the first Premiership club to go through a season on top of the table after every round, as the semi-finals are decided in Round 26.
Exeter's hopes of reaching the Gallagher Premiership play-offs for a seventh-successive season were effectively ended by Bristol on Friday night.
Exeter's rivalry with Saracens took another twist as their Premiership play-off hopes were dealt a potentially mortal blow by a 38-22 defeat.
A 21-point Joey Carbery display, in addition to a Damian de Allende try, saw Munster beat Exeter 26-10, sealing a European quarter-final spot.
Exeter toiled to a 13-8 Champions Cup Round of 16 first-leg win vs Munster at Sandy Park, but the Irish province remain in the tie.
A round-up of Saturday's Premiership games as Exeter come back to beat Bath, Gloucester suffer play-off blow, and Northampton remain in the play-off hunt.
We look through the potential contenders who the RFU could turn to once Eddie Jones leaves his role as England head coach...
Jack Nowell faces a battle to play again this season after sustaining a broken arm in England's Six Nations defeat by France.
Leicester Tigers scored seven tries in their 47-28 win against London Irish to maintain their lead at the top of the Gallagher Premiership on Saturday.
Exeter moved back into the Gallagher Premiership play-off zone with a 19-12 victory over Sale Sharks at Sandy Park.
Joe Simmonds' last-minute penalty ensured Exeter Chiefs beat Northampton Saints 34-31 in a thrilling match at Franklin's Gardens.
Exeter made hard work of beating 14-man Newcastle as a late penalty from Joe Simmonds ensured they won 15-14 in the Gallagher Premiership.
Dean Richards criticised the performance of the officials after his Newcastle Falcons side narrowly missed out on a win over Exeter.
Wasps, Sale Sharks and Exeter Chiefs all recorded victories in the Gallagher Premiership on Saturday, with Jimmy Gopperth's move to Leicester confirmed.
The action from Saturday's four Gallagher Premiership games as Leicester, Wasps, Saracens and Bristol triumphed.