Defending champions Northampton suffered a shock defeat to Gloucester, while Bath returned to top of the Premiership and Sale beat Leicester.
Bristol regained top spot in the Gallagher Premiership as centre Kalaveti Ravouvou scored two tries to underpin a 31-23 victory over champions Northampton at Ashton Gate.
Northampton bounced back from their derby disappointment in style as they trounced Sale while Newcastle earned their first Premiership victory in over a year.
Leicester made it three wins from four under Michael Cheika as they beat rivals and defending champions Northampton 24-8 on Saturday.
England wing Tom Roebuck scored two tries as Sale secured a breathless 31-27 bonus-point win over Gloucester in the Gallagher Premiership.
Leigh Halfpenny celebrated a first Gallagher Premiership try as Harlequins picked up a 28-14 bonus-point victory over Newcastle at Twickenham Stoop.
Michael Cheika's reign as Leicester head coach began in dramatic winning fashion as the Tigers claimed a 17-14 Gallagher Premiership victory at Sandy Park.
Mark Darbon has been appointed chief executive of the R&A and secretary of The Royal and Ancient Golf Club of St Andrews.
Northampton Saints sealed their first Premiership title for a decade, beating Bath 25-21 at Twickenham after Beno Obano's first half red card.
Bath fly-half Finn Russell says his side have to have trust and belief as they look to win their first Premiership title since 1996 when they take on Northampton in the final on Saturday at Twickenham.
Championship clubs have welcomed the approval of promotion to the Gallagher Premiership as a "new era" for the professional game in England.
Ahead of Saturday's Northampton Saints vs Bath Premiership final at Twickenham, Sky Sports looks back at the greatest witnessed so far...
All of the action from the final day of the Gallagher Premiership regular season, which saw the Play-Offs decided.
Northampton broke numerous records as they battered Gloucester 90-0 in the Gallagher Premiership.
Northampton fell short with a courageous second-half fightback as Leinster emerged 20-17 winners in their Investec Champions Cup semi-final at Croke Park
Harlequins ran in six tries as they beat Gallagher Premiership table toppers Northampton Saints 41-32 at Twickenham.
Northampton marched to a 40-17 Premiership bonus-point win over 14-man Leicester as they reinforced their status as table toppers on derby day.
Harlequins produced a stunning upset as they reached the Champions Cup semi-finals by beating French heavyweights Bordeaux-Begles 42-41.
Northampton charged through to the Investec Champions Cup quarter-finals with a 24-14 win over Munster.
It's been eight years since the Premiership had more than three clubs make it to the Champions Cup quarter-finals, but there remain six in play this season.
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