Connacht won in Dublin for the first time since September 2002, while Ulster maintained their 100-per-cent start in the PRO14 by beating Munster.
Glasgow and Edinburgh's postponed PRO14 derby clash rescheduled in a bid to reduce the risk of spreading Covid-19
Munster and Racing 92 lead the way after registering impressive away wins in round two of the Champions Cup.
Edinburgh kept their Champions Cup hopes alive as they fought back to defeat Sale Sharks 16-15 at the AJ Bell Stadium.
Glasgow have been forced to call off next week’s clash with Edinburgh after reporting four players have tested positive for coronavirus.
A lapse in concentration at the start of the second half proved to be the difference as Edinburgh fell to a hard-fought 13-8 loss to La Rochelle.
Bristol Bears and Clermont Auvergne get things underway in the Champions Cup on Saturday, while Toulon host Sale and Leinster travel to Montpellier.
Edinburgh fly-half Jaco van der Walt will make his Scotland debut in Saturday's Autumn Nations Cup clash against Ireland in Dublin.
Recap Monday's Guinness PRO14 action as Irish duo Munster and Ulster defeated Italy's Zebre and Scotland's Edinburgh respectively.
Recap all of Monday's PRO14 action as Leinster and Ulster maintained their 100 per cent starts in emphatic fashion, and Cardiff Blues won too.
The Dragons' PRO14 game with Edinburgh on November 23 has become their third match to be postponed due to coronavirus.
Blair Kinghorn is hoping to savour the joy of six after insisting Scotland's unbeaten streak is no fluke.
Exeter Chiefs will begin their Champions Cup title defence with a home fixture against Glasgow Warriors on Sunday December 13.
Ulster beat Glasgow to maintain their 100 per cent winning start to the season, while under-strength Edinburgh saw off Cardiff Blues.
Recap Sunday's PRO14 as Munster picked up their fourth win in succession with victory at the Dragons, and Edinburgh won at Scarlets.
Champions Cup holders Exeter Chiefs will face Glasgow Warriors and Toulouse in the 2020/21 pool stages.
Finn Russell is back for Scotland, while Duhan van der Merwe and Oli Kebble are set for their debuts against Georgia on Friday night.
Finn Russell has been recalled to the Scotland squad for the first time since the 2019 Rugby World Cup, after a period in exile.
Recap Saturday's Guinness PRO14 action as Irish trio Munster, Leinster and Ulster all pick up wins, as did the Cardiff Blues.
Recap the opening round of the Guinness PRO14 as Munster beat the Scarlets late on, while Connacht beat Glasgow in Galway.