Atalanta extended their unbeaten run to four matches in Serie A after edging to a 1-0 victory at Empoli.
A Gonzalo Higuain-inspired Napoli ran riot against Lazio while there were also wins for Inter Milan and Fiorentina.
Mario Balotelli hit the post as AC Milan lost 1-0 to leaders Inter in Serie A on Sunday, while Torino remain unbeaten.
Serie A champions Juventus saw their 47-match unbeaten home league record come to an end against Udinese.
Giacomo Bonaventura bagged a brace against his former club Atalanta as AC Milan won 3-1.
Fiorentina qualified for the Europa League while Stephan El Shaarawy scored his first goal in seven months for AC Milan.