Red-hot Fiorentina replaced Inter Milan as Serie A leaders by cruising to a 3-0 home victory over Atalanta on Sunday.
Barcelona beat Bayer Leverkusen 2-1 on Tuesday, while there were also Champions League wins for Bayern Munich and Valencia.
Bosnia look set to be without captain Edin Dzeko for next month's European Qualifer against Wales.
Juventus' poor Serie A start continued with defeat at Napoli, while Roma returned to winning ways against struggling Carpi.
Juventus could only draw 1-1 at home to Frosinone in Serie A on Wednesday, as leaders Inter Milan beat Hellas Verona 1-0.
A Gonzalo Higuain-inspired Napoli ran riot against Lazio while there were also wins for Inter Milan and Fiorentina.