Francesco Totti made his 600th Serie A appearance as Roma moved up to second spot with a 3-0 win over Chievo.
Paulo Dybala scored twice as Juventus thrashed Lazio 3-0 to take what could prove to be a decisive lead in Serie A.
Juventus moved a step closer to a fifth straight Serie A title after pulling nine points clear with a 4-0 win over Palermo.
Paul Pogba sustained Juventus' march towards a fifth straight Serie A title by completing a 2-1 comeback victory over AC Milan.
Goalkeeper Gianluigi Buffon added another record to his decorated career during Juventus' 4-1 win over local rivals Torino.
Napoli kept pace with fellow title-chasers Juventus after coming from behind to beat Chievo Verona 3-1 at the Stadio San Paolo.