Juventus needed an unfortunate own goal from Edoardo Goldaniga to squeeze past Palermo while Napoli beat Chievo.
Mauro Icardi inspired a superb comeback win for Inter as they beat Juventus 2-1 on Sunday, while Roma lost at Fiorentina.
Francesco Totti made his 600th Serie A appearance as Roma moved up to second spot with a 3-0 win over Chievo.
Paulo Dybala scored twice as Juventus thrashed Lazio 3-0 to take what could prove to be a decisive lead in Serie A.
Juventus moved a step closer to a fifth straight Serie A title after pulling nine points clear with a 4-0 win over Palermo.
Paul Pogba sustained Juventus' march towards a fifth straight Serie A title by completing a 2-1 comeback victory over AC Milan.