Friday 16 September 2016 00:05, UK
Three-time European champions Inter Milan were humbled at home in the Europa League by Hapoel Be'er Sheva, who gave Celtic a scare in their Champions League play-off before the Scots scraped through 5-4 on aggregate last month.
The Israel champions, making their Europa League group stage debut this season, were 2-0 winners as Miguel Virot and Maor Bar Buzaglo scored in the San Siro in Group K, while Southampton comfortably beat Sparta Prague 3-0.
Fellow big names Ajax fared better in Greece, where they came from behind to beat Panathinaikos 2-1 in Group G in a match which finished nine men playing 10.
Marcus Berg gave the hosts a fifth-minute lead but on-loan Chelsea forward Betrand Traore equalised before half-time and after Jairo Riedeweld scored the winner in the 67th minute things went downhill for the Greek side.
Ivan Ivanov was sent off for a second bookable offence - a fate which later befell Ajax's Hakim Ziyech - before Mubarak Wakaso was shown a red card for violent conduct in added time.
Goals from Alexandre Pato and Jonathan dos Santos saw Villarreal come from behind to beat FC Zurich 2-1 in Group L, while in Group J Fiorentina were held to a goalless draw by PAOK Salonika.
Zenit St Petersburg staged a dramatic comeback in their Group D clash with Maccabi Tel-Aviv, scoring four goals in the final 14 minutes to win 4-3.
The Russian club were trailing after goals from Haris Medunjanin (two) and Vidar Orn Kjartansson but Aleksandr Kokorin's scrambled finish gave them hope and the sending off of Eli Dasa nine minutes from time offered a lifeline.
Dasa's second yellow card led to Mauricio scoring via an indirect free-kick, Giuliano then equalised before Luka Djordjevic headed home in the second minute of added time.
Elsewhere in Group D, AZ Alkmaar were held to a 1-1 draw by 10-man Irish side Dundalk.
In Group F, Sassuolo marked their Europa League debut with a 3-0 win over seasoned campaigners Athletic Bilbao thanks to goals from Pol Lirola, Gregoire Defrel and Matteo Politano in the final half-hour.
Rapid Vienna also secured maximum points in that group with a 3-2 win over Racing Genk.
In Group A, Feyenoord's Tonny Vilhena scored the only goal to beat Manchester United while Ukrainian debutants Zorya were only denied a landmark first win by Fenerbahce defender Simon Kjaer's goal in the fifth minute of added time.
Group B's early pace-setters are APOEL and Olympiacos after wins over Astana (2-1) and Young Boys (1-0) respectively.
Anderlecht gained an early advantage in Group C as they beat FK Qabala 3-1 while rivals Mainz and St Etienne could only draw 1-1 with Robert Beric snatching an 88th-minute equaliser for the French club.
Diego Perotti scored an early penalty for Roma but they were pegged back by Marek Bakos' goal for Viktoria Pilzen in Group E, which is topped by Austria Vienna, who held on for 3-2 win over Astra Girgiu after Lukas Rotpuller's red card with 11 minutes to go.
