Michy Batshuayi continued his good start to life with Borussia Dortmund as he scored again in a 2-0 win over Hamburg.
Goalkeeper Rene Adler had a night to forget as he was involved in two howlers during Mainz's DFB Cup exit to Eintracht Frankfurt.
Schalke and Frankfurt reached the semi-finals of the German Cup after wins over Wolfsburg and Mainz respectively.
Ademola Lookman scored a dramatic late winner on his debut for RB Leipzig in a 1-0 victory at Borussia Monchengladbach in the day's late game.
In-form Bayer Leverkusen climbed to second in the Bundesliga following a 2-0 win at home to Mainz.
Naby Keita set RB Leipzig on their way to a 3-1 win over Schalke on Saturday evening.
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