There were Eredivisie wins for both Ajax and PSV on Saturday, while second-placed Heracles slipped to defeat.
Heracles Almelo moved to the top of the Dutch league with a 2-1 win over champions PSV Eindhoven at the Polman Stadion on Saturday.
Ajax's Anwar El Ghazi scored twice in a 4-0 win over ADO Den Haag that took them clear at the top of the Dutch league on Sunday.
Luuk de Jond rescued a point for champions PSV, while their were wins for Heracles and Roda JC.
Michael de Leeuw rescued a point for Groningen in a 1-1 draw with Twente in the Eredivisie on Wednesday, as NEC beat Excelsior 1-0.
AZ claim a Europa League place at the expense of Feyenoord, who were consigned to the play-offs for a place in Europe.