ADO Den Haag and Heerenveen will join Vitesse and Utrecht in the play-offs for the last Europa League spot despite mixed fortunes on the final day.
Former Eredivisie champions FC Twente have been relegated from the league after a thumping 5-0 defeat at Vitesse on Sunday.
Jorrit Hendrix's impressive late strike earned a point for Dutch champions PSV Eindhoven in a 2-2 draw against Roda.
PSV Eindhoven secured their 24th Eredivisie title after beating Ajax 3-0 on Sunday.
Remy Cabella scored twice as St Etienne extended their unbeaten run to nine games with a 3-0 win at Nantes.
PSV Eindhoven maintained their dominance of the Eredivisie with a 5-1 win over NAC Breda on Saturday.
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