The forward is expected to miss the rest of the season after suffering a broken right tibia during a clash with Lazio keeper Angelo Peruzzi.
The pair were involved in an accidental clash shortly after the half-hour mark as Saudati raced onto a through ball.
Saudati was stretchered from the field of play, and tests revealed the true extent of the injury that will require surgery.
Empoli president Fabrizio Corsi said: "The only problem is Saudati`s injury.
"His leg fracture will keep him out for the whole season.
"This is a bad day all round for us."