Sadio Mane suffered an injury scare less than two weeks before the start of the World Cup after being forced off during Bayern Munich's 6-1 demolition of Werder Bremen.
Manchester United will face Barcelona in their Europa League play-off in February, while Jose Mourinho's Roma will take on RB Salzburg.
Gerard Pique has announced his retirement from professional football and says his final game will be Barcelona's match against Almeria on Saturday.
Barcelona's Champions League exit prompts an angry reaction in Spain and ensures they will have to contest a Europa League round of 32 play-off.
Spanish prosecutors dropped all fraud and corruption charges against Brazil forward Neymar over his transfer to Barcelona from Santos in 2013.
Barcelona were knocked out of the Champions League before kicking a ball on Wednesday as Inter Milan's 4-0 win over Plzen left them with only a Europa League place.
Ousmane Dembele scored and provided assists for Sergi Roberto, Robert Lewandowski and Ferran Torres as Barcelona cruised past Athletic Bilbao.
Klay Thompson has revealed how the Golden State Warriors have taken inspiration from Barcelona's tiki-taka style.
Karim Benzema, Federico Valverde and Rodrygo were all on target as a dominant Real Madrid beat Barcelona 3-1 in El Clasico on Sunday, moving top of LaLiga.
For Barcelona head coach Xavi Hernandez, Sunday's El Clasico provides the perfect opportunity for his side to respond to a damaging result against Inter Milan.
Robert Lewandowski scored a last-gasp equaliser to keep Barcelona in the Champions League following a thrilling 3-3 draw at home to Inter Milan.
Atletico Madrid have re-signed Antoine Griezmann from Barcelona on a permanent deal.
Napoli thrashed Ajax in their Champions League meeting on Tuesday, with Barcelona and Atletico Madrid both suffering defeats.
Real Madrid beat city rivals Atletico but racist chanting directed at Vinicius Jr outside the Metropolitano marred the derby.
It was an unhappy return to Munich for Barca striker Robert Lewandowski, the Bavarians' second-highest all-time scorer, who left under a cloud in the summer.
Mathys Tel became Bayern Munich's youngest goalscorer but Stuttgart earned a late 2-2 draw in the Bundesliga on Saturday.
Raphinha scored his first Barcelona goal as the Catalans beat Sevilla. Also: Real Madrid and AC Milan won but Bayern Munich had to settle for a draw.
Chelsea sign former Arsenal striker Pierre-Emerick Aubameyang from Barcelona with Marcos Alonso going the other way after his Blues contract was terminated.