Jose Mourinho's Roma put themselves in the driving seat in their Europa League tie with a 2-0 first-leg win over Real Sociedad.
Arsenal have been drawn against Sporting Lisbon in the Europa League last 16, with Manchester United facing Real Betis.
Barcelona's lead over Real Madrid at the top of La Liga evaporated on after they were held to a 1-1 home draw in an ill-tempered clash with local rivals Espanyol.
Tammy Abraham finds the net for Roma but Jose Mourinho lashes out at an unnamed player, while Inter Milan thrash Bologna and Atletico Madrid lose again.
A controversial second-half penalty was the difference as Manchester United's Europa League campaign started with a 1-0 loss to Real Sociedad at Old Trafford.
Pierre-Emerick Aubameyang fired Barcelona back into second place in La Liga after a narrow victory at Real Sociedad.
PSG looked sluggish and apathetic as the Ligue 1 leaders slumped to a 3-0 defeat at Monaco, while Tammy Abraham scored twice in the Rome derby.
Tammy Abraham's penalty more than nine minutes into stoppage time ended Roma’s winless run as Jose Mourinho's scraped a 1-0 victory at 10-man Spezia in Serie A.
| # | Team | Pl | GD | Pts |
|---|---|---|---|---|
| 2 | R Madrid | 37 | 39 | 77 |
| 3 | A Madrid | 37 | 37 | 76 |
| 4 | Sociedad | 37 | 15 | 68 |
| 5 | Villarreal | 37 | 19 | 63 |
| 6 | Real Betis | 37 | 5 | 59 |
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