Ten-man Sevilla scored twice in the final minutes to salvage a 2-2 draw with Eibar in La Liga on Sunday.
Lionel Messi's two goals were not enough for Barcelona to salvage a win as they were held to a 2-2 draw at home to Valencia.
Barcelona once again moved five points clear of title challengers Atletico Madrid after a hard-fought 3-1 victory over Leganes.
Barcelona beat Levante to reach the Copa del Rey quarter-finals, but could yet be thrown out of the competition.
Real Madrid saw their La Liga title challenge slip further away after a shock 2-0 home defeat to Real Sociedad on Sunday.
Jonathan Calleri scored the only goal as Alaves climbed to fifth in La Liga with a 1-0 win at Real Sociedad, while Girona and Getafe drew 1-1 in the day's other game.
Antoine Griezmann dragged Atletico Madrid level with Barcelona at the top of La Liga, scoring twice to beat Valladolid.
Levante moved back into sixth after snatching a last-gasp 4-4 draw in a dramatic encounter at Eibar.
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