Cristiano Ronaldo bounced back from his red card against Valencia by opening the scoring in Juventus' 2-0 win over Frosinone.
Napoli missed the chance to go level with Serie A leaders Juventus after tumbling to a 3-0 defeat at Sampdoria.
Sevilla secured their place in the group stages of the Europa League with a 4-0 aggregate win over Sigma Olomouc.
Roma needed an 82nd-minute equaliser from Kostas Manolas to force a 3-3 draw against Atalanta at the Stadio Olimpico.
Hibernian have reached the third qualifying round of the Europa League after a nail-biting 1-1 draw against Asteras Tripolis in Greece.
Hibernian produced a second-half comeback to seal a 3-2 win against Asteras Tripoli in the first leg of their second round Europa League qualifier on Thursday.
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