A late fightback was not enough to see Xavi's Catalans make it through to the semi-finals, while the Special One has a date at the King Power.
Tammy Abraham's penalty more than nine minutes into stoppage time ended Roma’s winless run as Jose Mourinho's scraped a 1-0 victory at 10-man Spezia in Serie A.
Barcelona were held to a 0-0 home draw by Galatasaray in the first leg of their Europa League last-16 tie on Thursday as Rangers kept up their momentum.
Clubs from across Europe showed their support for Ukraine as the line-up for the Europa League and Europa Conference League last-16 was finalised on Thursday.
West Ham failed in a late bid to sign Atalanta striker Duvan Zapata on Deadline Day.