Atletico Madrid's recent wobble in form continued as they fell to a first defeat in 12 league games, while Bayern Munich were beaten in the Bundesliga.
Real Madrid continued to cling to the coat-tails of city rivals Atletico in the La Liga title race after winning 2-0 at home against Valencia.
Zlatan Ibrahimovic took his tally to more than 500 club goals as he scored twice to help AC Milan beat Crotone 4-0 and move back top of the Serie A standings on Sunday.
Real Madrid suffered a huge dent to their La Liga title ambitions following a surprise 2-1 defeat by Levante.
Real Madrid suffered a shock 2-1 defeat to third division Alcoyano to exit the Copa del Rey after extra-time on Wednesday night.
Real Madrid moved top of La Liga after a 2-0 home win over Celta Vigo with Lucas Vazquez and Marco Asensio on the scoresheet.
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