Sevilla took advantage of Barcelona dropping points to move top of La Liga with a 2-1 victory over 10-man Celta Vigo.
Valencia are still searching for their first win of the season after Iago Aspas struck eight minutes from time to rescue a 1-1 draw for Celta Vigo.
Former Manchester United forward Giuseppe Rossi's injury-plagued career has taken another negative turn with a positive doping test.
Thomas Lemar grabbed his first La Liga goal to help Atletico Madrid to a 2-0 win at Getafe.
Ten-man Atletico Madrid suffered a shock 2-0 defeat at Celta Vigo on Saturday.
Antonio Mohamed enjoyed his first win as Celta Vigo coach as a virtuoso display from Pione Sisto helped them to a 2-1 victory at Levante.
Lionel Messi scored twice - his first Barcelona's 6,000th La Liga goal - to help the reigning champions get off to a winning start with a 3-0 win over Alaves.
Spanish football captains will meet on Wednesday to discuss concerns over La Liga's plan to stage a league game in the US.
Goals, highlights, previews and more...
7 dedicated Sky Sports channels
Check out all the latest transfer news
All the gossip from the morning editions
The big new competition is here!
©2018 Sky UK