Porto welcome Atletico Madrid to Estadio do Dragao with a slender advantage in their UEFA Champions League tie.
Watch Wednesday night's clash live on Sky Sports Xtra
Porto welcome Atletico Madrid to Estadio do Dragao with a slender advantage in their UEFA Champions League tie.
The first leg of their first knockout round clash in Spain two weeks ago ended in a 2-2 draw, giving the 2004 champions the edge on away goals.
Jesualdo Ferreira's men had to come from behind twice in their opening meeting with Atletico as Lisandro's double cancelled out goals from Maxi Rodriguez and Diego Forlan.
Porto will be determined to avoid a hat-trick of last-16 exits having been knocked out of the competition at this stage in each of the last two seasons at the hands of FC Schalke and Chelsea, respectively.
Abel Resino's Atletico remain unbeaten during this season's Champions League campaign having progressed in second place behind Liverpool from Group D.
Concerns
Defender Cristian Sapunaru is a doubt with a leg injury, and is also one booking away from a suspension which would rule him out of the first leg of the quarter-final, should Porto progress.
Ferreira has further concerns over Fucile and Freddy Guarin, who have both been sidelined with ankle problems, while Nelson Benitez is struggling with a groin injury.
Atletico go into the game in good heart having halted city rivals Real's 10-game La Liga winning streak with a 1-1 draw at Santiago Bernabeu on Saturday, with star man Sergio Aguero setting up Forlan.
Luis Perea returned to action after a fractured cheekbone against Real and is available for European combat once again following suspension.
Maniche, Paulo Assuncao, Raul García and Mariano Pernia are one booking away from a ban, while Florent Sinama Pongolle (ankle) and Luis Garcia (hamstring) may miss out.