Real Madrid moved to the top of La Liga, level on points with rivals Atletico, after they won 3-0 at Cadiz, where Karim Benzema scored twice.
Benevento dented Juventus's Serie A title hopes on Sunday when Adolfo Gaich's second-half strike sealed a shock 1-0 victory in Turin.
Lautaro Martinez's late winner stretched Inter's winning run to eight games, while Cristiano Ronaldo answered his critics with a perfect hat-trick.
Lionel Messi equalled Pele's record of 643 goals for a single club after scoring for Barcelona against Valencia in La Liga on Saturday.
AC Milan restored their five-point lead at the top of Serie A with a 2-1 win at Sampdoria on Sunday.
Robert Lewandowski continued his hot goal-scoring streak with a hat-trick in Bayern Munich's 5-0 thumping of Eintracht Frankfurt.
Zlatan Ibrahimovic made a winning return to the AC Milan team as his quickfire double won the Milan derby, while Real Madrid and Barcelona suffered shock defeats.
AC Milan veteran Zlatan Ibrahimovic had a penalty saved but later scored as his side finished the Serie A season with a 3-0 win over Cagliari on Saturday.
Serie A’s hopes of successfully completing their season has received a boost after the Italian government relaxed some medical guidelines.