The FA have confirmed that Michail Antonio has withdrawn from the England squad for the upcoming matches against Germany and Lithuania.
No replacement will be called up for the West Ham winger, who picked up a hamstring injury during the 3-2 Premier League loss to Leicester on Saturday.
West Ham manager Slaven Bilic said after the Leicester game: "Michail played the whole game but his hamstring doesn't look great.
"It is very early to say, we don't know how long it is going to be.
"We have to assess him in the next couple of days. He might have to withdraw from England."
And a West Ham statement on Sunday night read: "Michail Antonio was withdrawn from the squad after being assessed by both the Hammers' and the England medical teams and will remain at Rush Green during the international break."
The 26-year-old Antonio has scored nine Premier League goals this season and has now been called into the England squad three times, but is still waiting to make his debut.
Despite his absence, manager Gareth Southgate has plenty of options in the wide attacking areas with Adam Lallana, Jesse Lingard, Alex Oxlade-Chamberlain, Nathan Redmond and Raheem Sterling all in the squad.
A squad of 25 players have reported to St George's Park ahead of a friendly with Germany in Dortmund on Wednesday and a World Cup qualifier at home to Lithuania on Sunday.
The squad are due to meet with manager Gareth Southgate on Monday morning before training in the afternoon.