Argentina closed in on a World Cup spot with a 1-0 win in Uruguay on Friday night.
Brazil moved within one win of qualifying for next year's World Cup by thrashing Uruguay 4-1 in Manaus, with Leeds' Raphinha scoring twice.
Lionel Messi was among the scorers as Argentina beat Uruguay 3-0 on Sunday, hours after Brazil were held to a goalless draw by Colombia.
Manchester United striker Edinson Cavani's Uruguay call-up for next month's World Cup Qualifiers has been cancelled.
Lionel Messi became Argentina's most capped international and scored twice as they beat Bolivia 4-1 to set up a Copa America quarter-final against Ecuador.
Uruguay and Paraguay secured their spots in the Copa America knockout stage as both won 2-0 in Group A, knocking Bolivia out of the tournament.
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