Peru have clinched the South American play-off spot in their bid to qualify for Qatar 2022, while Brazil broke Argentina's points record in their victory over Bolivia.
Raphina and Philippe Coutinho inspire Brazil to Paraguay win, Argentina dent Colombia's hopes; plus: Rodrigo Bentancur and Alexis Sanchez on target.
Brazil moved within one win of qualifying for next year's World Cup by thrashing Uruguay 4-1 in Manaus, with Leeds' Raphinha scoring twice.
Leeds' Raphinha made two of Brazil's comeback goals on his international debut as they recovered to win 3-1 in Venezuela.
Lionel Messi became Argentina's most capped international and scored twice as they beat Bolivia 4-1 to set up a Copa America quarter-final against Ecuador.