La Liga leaders Barcelona were held to a goalless draw by basement club Huesca on Saturday.
Getafe moved a step closer to earning Champions League football for the first
time in their history after beating Athletic Bilbao 1-0 on Sunday.
Zinedine Zidane suffered his first defeat since retaking the reins at Real Madrid as Valencia ran out 2-1 winners at the Mestalla.
Karim Benzema scored a last-gasp winner to secure victory and spare Real Madrid's blushes against La Liga bottom club Huesca.
Atletico Madrid's faint La Liga title hopes look to be over after they lost 2-0 at Athletic Bilbao on Saturday.
Espanyol forward Wu Lei became the first Chinese footballer to score in La Liga, scoring his side's third in a 3-1 win at home to Real Valladolid on Saturday.
A 1-1 draw did little to help Espanyol's fading European hopes or Huesca's slim survival chances.
Athletic Bilbao eased their relegation fears and heaped more trouble on rock-bottom Huesca with a 1-0 win in La Liga on Monday.
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