Red-hot Alexis Sanchez could be the scourge of Manchester United, says Ed Chamberlin

Another brilliant weekend of sport to look forward to with the return of the Premier League, Formula One's finale plus more autumn internationals with England facing a must-win game against Samoa on Saturday.

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What a shame Stuart Lancaster doesn't get the chance to right the wrongs and prove a point to his critics with another crack at either the All Blacks or South Africa in a three-match series. The game at Twickenham kicks off at 7pm on Sky Sports 2. 

Before that, Arsenal against Manchester United is some way to get things going on Saturday Night Football. Both have big questions to answer and it's a brave punter that goes wading in on either Arsenal at 23/20 or Man Utd at 11/5. The safest option of late has been to simply back Alexis Sanchez to score! He's 5/4 to score again on Saturday evening.

With the way they are both playing, and defending, it's hard to see this game being anything other than a thriller and it will be fascinating to see who comes out on top as both their seasons teeter on the brink right now.

We'll be at Selhurst Park for Super Sunday, which is a ground I love going to. Win, lose or draw, the noise from the home fans is relentless. The place was rocking the last time these two met on Monday Night Football on May 5th 2014.

Live Ford Saturday Night Football

One will always remember that famous Martin Tyler line "Liverpool have caved in" as they squandered a three-goal lead in the final 11 minutes to see their Premier League title hopes suffer a fatal blow. Liverpool will be out for revenge.

Part two of Super Sunday sees Tottenham Hotspur go to a Hull City desperately in need of a win after only two victories from their last nine games (D2, L5). Hull have problems of their own, hovering just two points above the relegation places having lost their last two games without scoring and without a win in their last four.

Monday Night Football provides a chance to see Ronald Koeman's Southampton first hand away at Aston Villa. I was with Koeman at the National Football Museum in Manchester on Thursday night and his feet remain firmly on the ground.

However, 25 points from their opening 11 games is the Saints' best start to a top-flight season in their history. Thirty-two teams have started this well in previous Premier League campaigns and only five have failed to go on to finish in the top four. Southampton are down to 2/1 with Sky Bet to achieve a top-four finish, having begun this season as 100/1 outsiders to finish in the Champions League places. I wonder if Jamie Carragher may change his mind ...

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Back to the game, and what an important one this is for Southampton as they try to keep their momentum going into the crucial ten days with matches against Manchester City, Arsenal and United on the horizon. Monday night sees the worst attack and best defence in all four English League divisions taking each other on. Villa have scored only five goals, Southampton have only conceded five. It's Villains against Saints.

Horse Racing

This weekend is all about quality rather than quantity in the Champion Hurdle trials. A chance to enjoy watching The New One and Faugheen strut their stuff at Haydock and Ascot. The betting opportunities lie elsewhere.

The Betfair Chase looks very difficult to call. I sense a changing of the guard in the chasing div