Eric Dier has told his Tottenham team-mates to cope with the absence of Harry Kane and Dele Alli.
Dier returned as a substitute in Sunday's 2-1 win at Fulham after spending over a month out following surgery to remove his appendix.
But striker Kane is now out until March with an ankle injury and Alli suffered a hamstring problem which requires a scan, the results of which are likely to come in the next few days.
Dier said: "Every team gets injuries; we have to deal with it, we're not sulking about it or feeling sorry for ourselves."
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Harry Winks' stoppage-time header earned a crucial victory for Spurs over Fulham as they regained their four-point advantage over fourth-placed Chelsea.
Mauricio Pochettino's men are nine points behind leaders Liverpool and trail Manchester City by four.
Until Winks' late intervention, Kane's absence and that of Heung-Min Son, on international duty with South Korea, appeared to have left them short in the final third and therefore at risk of dropping points at a crucial stage of the season.
Their persistence and an unlikely contribution from Georges-Kevin Nkoudou in creating Winks' goal secured victory and proved they have options.
Dier added: "It's not a question of if we can cope without Harry or not. Harry's one of the best strikers in the world, any team would feel the loss if Harry wasn't playing, so we have to find a solution and move on.
"Injuries happen in football and that's why you have a squad and not just 11 players.
"It was a good start (to life without him). People are going to be talking about it when he's injured but we've just got to get on with it.
"Harry will be doing his best to get back as soon as possible and it's down to the team and the squad to rally and carry on.
"Fernando's a very good player. He has very good qualities. We need to give him the service he needs to demonstrate his qualities. We can do that and he can (also) help the team."