Manager Ronald Koeman believes Southampton can continue to thrive this season and is relishing the chance to take on the Premier League big boys.
Despite the likes of Luke Shaw, Adam Lallana, Dejan Lovren and Rickie Lambert leaving in the summer, Koeman has begun his reign in style and the Saints currently sit in second place in the Premier League ahead of Sunday's clash with Manchester City at St Mary's, live on Sky.
The Dutchman said: "We try to play game by game and prepare ourselves in the best way for every game.
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"We know our possibilities but we have played 12 games now and I didn't see one team better than us in these 12 games and we played against Liverpool and Tottenham. Maybe Sunday but we will see.
"(Man City) will take this game very seriously. They know that we are strong.
"One of (our) qualities is the organisation in the team and if you don't have that organisation it's not possible to concede only six goals in 12 games.
"They know, for sure, they have to be good to win against us and the challenge for us is to beat a good team in the Premier League.
"We have the supporters at our back and that will be important for Sunday."
We know if we like to do something special this season then we have to win these kind of games that we have to play.
Southampton's clash with the champions kicks off an intimidating run of nine league fixtures that includes two games against both Arsenal and Manchester united as well as a home clash with Chelsea.
Koeman added: "I think if we would like to do better than last season, this period is important because we played nine games until January 1 and that's difficult, a difficult programme.
"Everybody knows there isn't an easy game in the Premier League and you have to be prepared every game.
"We know if we like to do something special this season then we have to win these kind of games that we have to play."
Watch Southampton v Manchester, Sunday 1.30pm, Sky Sports 1