Now the fixtures have been released we have picked out ten clashes that immediately catch the eye.
MANCHESTER UNITED v CHELSEA (Saturday, August 24)
These two heavyweights do not have to wait long for their first duel of the campaign. David Moyes' first Premier League home game at Old Trafford is against Jose Mourinho's men on the second weekend of the season. Both meetings of these teams ended in away wins in 2012-13, with Moyes' new beginning and Mourinho's return adding extra spice to this.
MANCHESTER CITY v MANCHESTER UNITED (Saturday, September 21)
Fans of the Manchester rivals had to wait nearly four months for the first derby last season - this time around just four games will have been played by the time new boss Manuel Pellegrini's men take on their closest rivals at the Etihad Stadium. Again, the away team was victorious in each match last season.
SUNDERLAND v NEWCASTLE (Saturday, October 26)
Sunderland took four points off their fellow strugglers last season - which proved decisive in their survival battle. Paolo Di Canio's second game in charge was a 3-0 win on Tyneside, the Black Cats' biggest win there since 1979 - and Joe Kinnear and Alan Pardew will be plotting revenge in the first meeting of the north-east rivals.
CARDIFF v SWANSEA (Saturday, November 2)
Another explosive derby. The Premier League's first Welsh derby will take place at the Cardiff City Stadium. The Bluebirds' Championship-winning campaign was built on the best home record in the league - and they will need to stay strong in front of their own support to improve their survival chances. Michael Laudrup's League Cup winners will provide tough opposition.
ARSENAL v CHELSEA (Saturday, December 21)
Chelsea did the double over their London rivals last season - but Arsenal finished the season strongly and, with Arsene Wenger promised investment to strengthen his squad, this Emirates Stadium clash should have lots going for it. One of the final round of fixtures before Christmas, it could be a cracker.
LIVERPOOL v EVERTON (Saturday, January 28)
Everton manager Roberto Martinez will be hoping for better luck in derby matches than predecessor David Moyes had over recent seasons. The Toffees have go back to 2010 for their last win over their city rivals and, with both teams again hoping to end their European exile, three points from this game could prove decisive at the end of the season.
MANCHESTER CITY v CHELSEA (Saturday, February 1)
The second and third favourites for the title go head-to-head at the Etihad Stadium. Mourinho, who maintains he was unconcerned at being overlooked by City when they were seeking a manager, had an impressive record in games against City in his first spell as Chelsea boss and will be hoping that continues against Pellegrini's men.
TOTTENHAM v ARSENAL (Saturday, March 15)
These sides have failed to disappoint when facing each other recently - their last six derbies have yielded 31 goals. Spurs' quest to beat their north London rivals to a Champions League place ended in disappointment against last season - and their fans will be hoping Gareth Bale will still be around when they meet again as the season enters the home straight.
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