Tony Pulis remains without a win as Sheffield Wednesday manager but his players held high-flying Reading to a 1-1 draw despite playing for an hour with 10 men.
After Callum Paterson gave the Owls an early lead at Hillsborough, teenage midfielder Liam Shaw became the club's fifth player in nine games to be shown a red card following a crude challenge on Omar Richards.
Lucas Joao went on to level matters on the stroke of half-time with a 13th goal of the season against his old club, but a reorganised Wednesday refused to be breached during a determined second-half display.
Reading kept possession in confident fashion during the opening exchanges and Joao might have broken the deadlock in the sixth minute when he was released through the left channel after an incisive pass by Richards.
But the Portuguese striker dragged the opportunity across the face of Joe Wildsmith's goal.
Instead, it was the hosts that forged in front from their first attack of the match in the 12th minute following an impressive flowing move.
Kadeem Harris' sweeping diagonal pass sent Adam Reach charging down the left flank and his excellent cross to the far post was expertly headed back across goal by Paterson into the bottom corner.
It was the Scotland international's second goal of the season and he almost claimed a third just two minutes later when he directed another header - from Liam Palmer's right-wing cross - inches wide.
That scare seemed to galvanise the visitors back into action with Michael Olise's curling 30-yard free-kick thumping against the base of an upright and, on the half-hour mark, the Royals gained their numerical advantage when Shaw clattered into Richards close to the halfway line.
The rest of the half was one-way traffic with Wildsmith displaying heroic reflexes to tip over a firmly-struck Alfa Semedo effort and a stretching Reach somehow diverting Richards' powerful drive over his own crossbar on the goal line.
Wednesday managed to hold out until the 44th minute when Ovie Ejaria was fouled close to the left byline and then floated the resulting free-kick to the far post where Joao headed in.
Pulis made a triple substitution at the interval and also dropped Paterson back into midfield as the more energetic Harris pushed forward into the lone striker role instead, with his players containing the visitors much more effectively after the restart.
An Olise free-kick brushed the top of the net just past the hour, while Michael Morrison also headed wide and Ejaria fired off target from distance and had a second attempt from the edge of the box shovelled away by Wildsmith.
Reading then camped in the hosts' half for the final 10 minutes but could not force a winner with Josh Laurent tumbling in the box but seeing his strong shout for a penalty turned down.
What the managers said...
Sheffield Wednesday's Tony Pulis: "They are a good side and have game changers in their team, who are very dangerous when they get good possession. The sending off was a reckless challenge and you can't do that. I understand why the referee gave the red card and we've got to be a lot more understanding of the rules in a lot of ways, because that's our fifth red card of the season, which is really poor.
"Half-time then gave us a chance to make changes and make us more resilient and, in the second half, the players worked so hard. They lack certain things but they are a really honest group who are buying into what we are trying to do, although we had a bit of luck with certain decisions. I thought the referee was going to give two penalties and I'm absolutely delighted he didn't."
Reading's Veljko Paunovic: "I did not look back at the penalty appeals after the game and I won't complain about officiating. Like ourselves, everyone needs to be accountable for their own actions and it's difficult to be objective when you are involved, but I thought two penalties were very possible. But we will use this disappointment and channel it into energy when we finally play in front of our fans again on Saturday. I don't want anything to affect that and we have got to bounce back again.
"On the one hand, I was proud of this performance because the team did everything we had to do in this kind of game. We had good possession and created opportunities. But, on the other hand, I am disappointed that we didn't get the result because we were the team who wanted to get most out of this game."
Win £250,000 for free on Tuesday!
Do not miss your chance to land the £250,000 in Tuesday's Super 6 round. Play for free, entries by 3:00pm.