Wayne Rooney could make his first-team return in Manchester United's FA Cup quarter-final replay at West Ham.

The United and England captain played 61 minutes for United's U21s on Monday in his first outing since sustaining a knee injury in their February defeat at Sunderland.

United will be looking to keep their only hopes of silverware alive when they travel to the Boleyn for what is set to be the final FA Cup game held at West Ham's historic ground.

The Hammers, who last lifted the trophy back in 1980, will want to give Upton Park a fitting send off before they move to the Olympic Stadium next season.

In what will no doubt be a special atmosphere, Slaven Bilic's side will hope to hold their nerve after being denied a semi-final tie in controversial circumstances in the first meeting at Old Trafford, following Anthony Martial's late equaliser.

Team news

West Ham will be without Diafra Sakho after manager  Bilic revealed the Senegal striker suffered a minor knee injury in training which is expected to keep him out for a week.

Andy Carroll is likely to retain his spot in attack having scored a hat-trick in Saturday's draw with Arsenal, and Bilic has insisted he will not rotate his squad despite a trip to Premier League leaders Leicester at the weekend.

Phil Jones, who last featured for the seniors in January's victory over Swansea, completed the full duration of Monday's match and will also be assessed ahead of the trip to Upton Park.

Fellow defender Timothy Fosu-Mensah will also be assessed before the trip to the Boleyn after he was forced off in the second half of Sunday's disappointing defeat at Tottenham.

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This is the ninth time these sides have been drawn in the FA Cup - the previous eight have alternated between West Ham progressing twice and Man United progressing twice.

The Red Devils have progressed the last two times they've faced West Ham in the FA Cup, meaning West Ham would go through if the sequence was to continue.

Louis van Gaal's side were eliminated at this stage last season, to eventual FA Cup winners Arsenal.

West Ham have reached the quarter-final stage of the FA Cup for the first time since 2011, when they were eliminated by eventual runners-up Stoke.

The Hammers are winless in their last 11 competitive meetings with Manchester United (D5 L6), but their last victory was in a domestic cup QF tie at Upton Park (League Cup in November 2010).

Manchester United have only failed to score in two of their last 15 away trips to Upton Park to face West Ham United.

Carroll has scored more goals in his last three West Ham appearances (4) than he did in his previous 22 apps for the club this season (3).

Dimitri Payet has had a hand in 23 goals in all competitions for West Ham this season (12 goals, 11 assists) - 13 more than any other player at the club.

Charlie's prediction

I fancied West Ham before the weekend and I've got no reason to change my mind. If United think they played well at Spurs, with one shot on target, they don't know much about winning football matches.

Andy Carroll was brilliant against Arsenal but I really don't know why people are on the Euros bandwagon after one performance, although he'll be relishing going up against Chris Smalling and Daley Blind.

United have never enjoyed going to West Ham, even under Sir Alex Ferguson, so I'm going to back the home side, with Payet relishing the big game again.

Charlie predicts: 2-0 and Payet to score first (60/1 with Sky Bet)

Betting

West Ham are marginal favourites with Sky Bet at 6/4 for the victory, with Manchester United given a 17/10 chance while another draw and extra-time in priced at 12/5. Louis van Gaal's men are, however, shorter odds in the FA Cup outright at 4/1 to the Hammers' price of 9/2, with Everton currently 9/4 favourites. Marcus Rashford is considered the 5/1 favourite in the first goalscorer betting despite the expected availability of Wayne Rooney (11/2), while Andy Carroll is 80/1 for a repeat of his hat-trick heroics against Arsenal.