Barcelona were made to work for their win against third-place Getafe in La Liga on Saturday while PSG were held 4-4 by Amiens in France.
Robert Lewandowski scored another double to send Bayern Munich through to the DFB-Pokal quarter-finals as Lazio missed the chance to go second in Serie A.
Karim Benzema scored for the first time in a Madrid derby at the Bernabeu as Real Madrid beat Atletico Madrid 1-0.
Bayern Munich hammered Borussia Dortmund 4-0 at the Allianz Arena, while Real Madrid also hit four against Eibar to keep up with the pace at the top of La Liga.
Romelu Lukaku's goal was not enough for Inter Milan as they missed out on the chance to steal top spot in Serie A from Juventus.
Marseille kept their hopes of qualifying for next season's Champions League alive with a 3-1 win at struggling Guingamp.
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