Arsenal will be out for revenge for their Carabao Cup final defeat as they host Man City, live on Sky Sports Premier League on Thursday.
City strolled to a 3-0 win at Wembley on Sunday, and the Premier League leaders are back in north London on Thursday for a replay of the final as they look to consolidate their position at the top of the table.
Arsenal manager Arsene Wenger says he is not worried about his future and is solely focused on Thursday's match.
"Honestly, my position is the last worry I have, my focus is to get the team ready for the game."
Pep Guardiola says City's priority remains on securing the Premier League title and insists it is not a foregone conclusion, despite their 13-point advantage and Thursday's game in hand.
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"We are fighting for the most important title of the season by far - the Premier League," Guardiola said at his pre-match press conference.
"We have still to win six games and when you think about Arsenal, Chelsea, Tottenham, Manchester United and our away games like Stoke, who are playing to avoid relegation [it will be hard]."
Nacho Monreal will miss the clash after sustaining an injury in Sunday's Carabao Cup final.
The Spain international was forced off in the 3-0 loss to City with a back problem, which has also ruled him out of Sunday's trip to Brighton.
Wenger has no other fresh injury concerns and can recall January signing Henrikh Mkhitaryan, who was cup-tied at Wembley.
City are set to be without Raheem Sterling and Fernandinho for Thursday's trip. Forward Sterling is again doubtful after missing two games with a muscular problem while midfielder Fernandinho is definitely out with a hamstring strain.
Left-back Fabian Delph serves the second match of a three-game suspension while Benjamin Mendy (knee) is a long-term absentee.
Arsenal have won just two of their last 11 Premier League meetings with Manchester City, drawing five and losing four. Indeed, both teams have found the back of the net in eight of their last nine clashes in the Premier League.
City have won only one of their 20 Premier League away games against Arsenal (D7 L12) - winning 2-0 under Roberto Mancini in January 2013.
City could become the first side to beat Arsenal three times in the same season since Chelsea in 2005-06 - those three defeats also all occurred at different grounds.
Manchester City's points total of 72 from 27 games is the most ever set by an English top-flight side at this stage of the season (3 pts for a win). If they win this game, it'll match Arsenal's Premier League tally from last season (75 points from 38 games).
Manchester City are Sky Bet's 5/6 favourites for the victory with Arsenal up against odds of 16/5 despite home advantage, while the draw is priced at 14/5. The Gunners are currently 18/1 to secure a top-four finish, with the Europa League considered their most likely route back into the Champions League at 5/1 for them to lift the trophy.
Sergio Aguero heads the goalscorer betting and is enhanced from 7/2 to 4/1 to net first in Sky Bet's Price Boosts, while Pierre-Emerick Aubameyang is considered the hosts' main threat at 11/2 to net first.