Manchester City forward Sergio Aguero has been banned for three matches for violent conduct and will miss the Manchester derby on September 10.
Aguero was cited by the Football Association on Tuesday after appearing to elbow West Ham defender Winston Reid during his side's 3-1 victory at the Etihad Stadium on Super Sunday.
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The 28-year-old, who has scored six times so far this season, has unsuccessfully appealed his charge and his absence will come as a major blow to manager Pep Guardiola.
Aguero will miss the Premier League clashes with local rivals United at Old Trafford - live on Sky Sports 1 HD from 12.30pm - and Bournemouth on September 17.
The Argentina international will also miss the EFL Cup third-round tie against Swansea at the Liberty Stadium on September 21.
However, he will be free to make his return from suspension away at Swansea in the Premier League three days later.
Sky Sports pundit Jamie Carragher believes there was never any doubt Aguero would receive a ban following the incident.
The former Liverpool defender admitted the Manchester derby will see the country's current two best teams face each other, but thinks the City striker's absence will tarnish the game.
"As soon as it happened you think he's got a problem there," Carragher told Sky Sports News HQ. "It's a massive game coming up.
"For a neutral you'd all like to see the best players playing against each other - the two top teams in the country at the moment.
"I think he's one of the best players we've got in the Premier league. But, rightly so, he was always going to get a ban when he put an elbow in someone's face."
City have made a 100 per cent start to life under Guardiola and currently sit top of the Premier League on goal difference ahead of Chelsea and United.