Team news and ways to follow Shkendija Tetovo vs Tottenham on Thursday (kick-off 7pm).
Jose Mourinho may field a different team than planned in Macedonia in light of Spurs' postponed Carabao Cup third-round game at Leyton Orient on Tuesday, where Joe Hart had been in line for his Tottenham debut.
Sergio Reguilon, who signed from Real Madrid on Saturday, will not be part of the squad, with Gareth Bale also missing until October.
Mourinho: Europa team will be different from Orient
Tottenham boss Mourinho said he would not be tempted to field the same line-up which had been due to take to the field at Leyton Orient on Tuesday when they travel to North Macedonia on Thursday, on the back of an unexpected extra two days' rest for his squad.
"The team that was supposed to play last night is different to the team that plays tomorrow," Mourinho said. "The main reason is that we played last Sunday at Southampton and one thing is Sunday, Tuesday and another is Sunday, Thursday.
"So this is a normal situation for a football player of this level to have three days rest and to play again on Thursday. Normal.
"It's not normal to play Sunday and then play Tuesday so obviously the teams are going to be different. The main reason is health and conditions to perform.
"Is the Europa League a competition that we want very much to get to the group stage. Yes it is."